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P. acnes is a Gram-positive pleomorphic diphtheroid-like anaerobic bacillus, and it is part of the normal skin flora. 2, 5 As identified previously, shunt infection with P. acnes frequently results in a mild clinical picture, can be associated with an abdominal pseudocyst and infections occur in the older child and adolescent. 4 With improved diagnostics, including extended culture protocols, P. acnes has been specifically recognized as a dominant organism in infections involving shoulder prostheses [ 14–23 ]. Yet, there has been a paucity of data on the clinical and microbiologic characteristics of such infections. Both early and delayed infection were observed in our patient population, which suggests that P. acnes may remain latent for several months before an infection is diagnosed. Early infection was associated with local joint inflammation more frequently than delayed infection.

P acnes infection

We present a case of P. acnes empyema complicating medical thoracoscopy. P. acnes bacterium was rarely reported in the literature to cause infection in the subdural space. Cultures positive for P. acnes may sometimes represent a false-positive result due to contamination which makes the diagnosis of a true infection often challenging . Propionibacterium acnes detection in culture media was previously considered a contamination but recently its infectious role was discovered in post-spinal surgery infections. P. acnes might be introduced during surgery. Its diagnosis is based on non-specific clinical signs, image indications of infection, and the conclusive microbiological sign. Furthermore, its diagnosis is difficult because Berthelot P, Carricajo A, Aubert G, et al.

ACTA DERMATO-VENEREOLOGICA - Medicaljournals.se

2016-06-29 · Propionibacterium acnes is well-established as a possible etiologic agent of prosthetic joint infections (PJIs). Other Propionibacterium spp.

Jan Faergemann Göteborgs universitet

Raising awareness that this slow-growing microorganism can cause prosthetic valve endocarditis, mainly in male patients, is important and we support the suggestion to incubate the cultures for a longer period of time (10–14 days). P. acnes is usually more likely to be pathogenic when growing in more than one specimen or when cultured from a deep intraoperative specimen [ 3 ]. Furthermore, postcraniotomy infection caused by P. acnes is relatively uncommon, but when it occurs, it can be associated with significant complications and can become life-threatening [ 4 ]. puncture for collection. P. acnes is a commoncontaminant ofanaerobicbloodcultures (11, 44, 46). Of151 patients with blood cultures positive for P. acnes, only 1 had significant infection (46).

Cultures positive for P. acnes may sometimes represent a false-positive result due to contamination which makes the diagnosis of a true infection often challenging . Propionibacterium acnes detection in culture media was previously considered a contamination but recently its infectious role was discovered in post-spinal surgery infections.
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Lapins J Albert HB, Kjaer P, Jensen TS, Sorensen JS, Bendix T, Manniche C Modic Propionibacterium acnes infected intervertebral discs cause vertebral bone marrow Propionibacterium acnes infection induces upregulation of inflammatory genes and cytokine secretion in prostate epithelial cells. Propionibacterium acnes (P. acnes), sedan år 2016 Cutibacterium acnes (C.

The present rat model suggests that complications such as chronic inflammation may be induced by P. acnes infection.
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Accepterade mikrobiologiska abstracts infektionsveckan

2016-06-29 · Propionibacterium acnes is well-established as a possible etiologic agent of prosthetic joint infections (PJIs). Other Propionibacterium spp. have occasionally been described as a cause of PJIs, but this has not previously been the case for P. avidum despite its capacity to form biofilm. Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry. While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity. P. acnes is susceptible to a wide range of antimicrobial compounds and chemicals making it relevant when testing antimicrobial efficacy of substances. Notes.